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Search Results for " Janus kinase "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T38624	Fosifidancitinib		JAK
	Fosifidancitinib is a potent inhibitor of JAK 1 and JAK 3.		JAK
T3080	Pyridone 6	Janus-Associated Kinase Inhibitor I,JAK Inhibitor,CMP 6,JAK Inhibitor I	Tyrosine Kinases , JAK
	Pyridone 6 (JAK Inhibitor)(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM); displaying significantly weaker affinities (130 nM to 10 mM...		Tyrosine Kinases , JAK
T11710	JAK-IN-5		JAK
	JAK-IN-5 is a JAK inhibitor.		JAK
T6217	LFM-A13		PLK , JAK , BTK
	LFM-A13（IC50=2.5 μM）, a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.		PLK , JAK , BTK
T3069	AZD-1480		JAK
	AZD1480 is a novel ATP-competitive JAK2 inhibitor (IC50: 0.26 nM), selectivity act against Tyk2 and JAK3, and to a smaller extent against JAK1. AZD1480 has been used in trials studying the treatment of Solid Malignancies...		JAK
T6790	BMS-911543	BMS911543	Tyrosine Kinases , Histone Methyltransferase , JAK
	BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.		Tyrosine Kinases , Histone Methyltransferase , JAK
T4210	SAR-20347	SAR20347	Tyrosine Kinases , JAK
	SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).		Tyrosine Kinases , JAK
T5091	FM-381	FM381	JAK
	FM381 is a potent covalent reversible inhibitor of JAK3. FM-381 has an IC50 of 127 pM for JAK3, with 410, 2700 and 3600-fold selectivity over JAK1, JAK2 and TYK2, respectively.		JAK
T5492	JAK3-IN-6		JAK
	JAK3-IN-6 is irreversible Janus Associated Kinase 3 (JAK3) inhibitor, with an IC50 of 0.15 nM		JAK
T2156	WP1066		Apoptosis , JAK , STAT
	WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3. WP1066 has been used in trials studying the treatment of Melanoma, Bra...		Apoptosis , JAK , STAT
T6122	CEP-33779	CEP33779	JAK
	CEP-33779 is a novel and selective inhibitor of JAK2 with an IC50 of 1.8±0.6 nM.		JAK
T14331	Gusacitinib	ASN-002	JAK , Syk
	Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).		JAK , Syk
T8546	BD750		JAK , STAT
	BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in mouse and human T cells, respectively)		JAK , STAT
T39113L	Povorcitinib phosphate		JAK
	Povorcitinib phosphate is a selective JAK1 inhibitor and can be used in studies about the treatment of cutaneous lupus erythematosus and Lichen planus.		JAK
T6838	FLLL32		Apoptosis , JAK , STAT
	FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).		Apoptosis , JAK , STAT
TQ0010	Brepocitinib	PF-06700841	Tyrosine Kinases , JAK
			Tyrosine Kinases , JAK
T10431	Golidocitinib	AZD4205	JAK
	Golidocitinib (AZD4205) is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).		JAK
T1929	Filgotinib	GLPG0634	Tyrosine Kinases , JAK
	Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.		Tyrosine Kinases , JAK
T5382	Ritlecitinib	PF-06651600	JAK
	Ritlecitinib (PF-06651600) is a potent JAK3-selective inhibitor (IC50: 33.1 nM).		JAK
TQ0037	Abrocitinib	PF-04965842	JAK
	Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).		JAK
T6309	AZ960	AZ 960	Apoptosis , Virus Protease , JAK , Parasite
	AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).		Apoptosis , Virus Protease , JAK , Parasite
T6020	Pacritinib	SB1518	FLT , Tyrosine Kinases , JAK
	Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).		FLT , Tyrosine Kinases , JAK
T17019	TCS 21311	NIBR3049	GSK-3 , JAK , PKC
	TCS 21311 (NIBR3049) is an effective and highly selective inhibitor of JAK3 (IC50: 8 nM). TCS 21311 inhibits PKCα, PKCθ, and GSK3β (IC50s: 13, 68, and 3 nM, respectively). It displays >100-fold selectivity over JAK1, JAK...		GSK-3 , JAK , PKC
T2378	RGB-286638 free base		GSK-3 , MEK , JAK , CDK
	RGB-286638 free base is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin T1-CDK9/cyclin B1-CDK1/cyclin E-CDK2/cyclin D1-CDK4/cyclin E-CDK3/p35-CDK5 respectively; less potent against cyclin H-CDK7 a...		GSK-3 , MEK , JAK , CDK
T3065	TG101209		Apoptosis , FLT , c-RET , JAK , Autophagy
	TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.		Apoptosis , FLT , c-RET , JAK , Autophagy
T22416	RO495	CS-2667	Tyrosine Kinases , JAK
	RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assays		Tyrosine Kinases , JAK
T3072	XL019		Apoptosis , FLT , JAK , PDGFR
	XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.		Apoptosis , FLT , JAK , PDGFR
T3068	AT9283	J-504568	Apoptosis , FLT , JAK , Bcr-Abl , Aurora Kinase , Autophagy
	AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).
T7503	Upadacitinib	ABT-494	JAK
	Upadacitinib (ABT-494) (ABT-494) is a selective Janus kinase (JAK) 1 inhibitor, which is being studied for the treatment of several autoimmune disorders in the IC50 of 43 nM.		JAK
T12266	Ilginatinib	NS-018	Tyrosine Kinases , JAK
	Ilginatinib (NS-018) is a highly active and orally bioavailable inhibitor of JAK2.		Tyrosine Kinases , JAK
T6321	Tofacitinib	Tasocitinib,CP-690550	ROCK , Apoptosis , JAK , Src
	Tofacitinib (Tasocitinib) is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis.		ROCK , Apoptosis , JAK , Src
T3042	JAK2 Inhibitor V	JAK2 Inhibitor V Z3,Z3	JAK
	JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.		JAK
T2487	Cerdulatinib	PRT2070,PRT062070	Tyrosine Kinases , JAK , Syk
	Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.		Tyrosine Kinases , JAK , Syk
T12427	Brepocitinib P-Tosylate	PF-06700841 P-Tosylate	JAK
	Brepocitinib P-Tosylate (PF-06700841 P-Tosylate) is a potent dual inhibitor of Janus kinase 1 (JAK1) and TYK2 (IC50s of 17 nM and 23 nM, respectively).		JAK
T15096	Delgocitinib	JTE-052,Corectim（Delgocitinib）	Tyrosine Kinases , JAK
	Delgocitinib (JTE-052) is a specific JAK (Janus kinase) inhibitor with IC50 values of 2.8, 2.6, 13, and 58 nM for JAK1, JAK2, JAK3, and Tyk2 respectively. Delgocitinib is involved in various inflammatory and autoimmune d...		Tyrosine Kinases , JAK
T3998	Itacitinib	INCB39110,INCB039110	JAK
	Itacitinib (INCB039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.		JAK
T14687	Deucravacitinib	BMS-986165	Tyrosine Kinases , JAK , IFNAR , Interleukin
	Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases. Which selectively bi...		Tyrosine Kinases , JAK , IFNAR , Interleukin
T3076	GLPG0634 analog	GLPG0634 analogue	Tyrosine Kinases , JAK
	GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.		Tyrosine Kinases , JAK
T2638	Gandotinib	LY2784544	VEGFR , FGFR , FLT , JAK
	LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM). The selectivity is higher 8- and 20-fold than JAK1 and JAK3.		VEGFR , FGFR , FLT , JAK
T2636	Decernotinib	VX-509,VRT-831509	Tyrosine Kinases , JAK
	Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.		Tyrosine Kinases , JAK
T7123	AMG-47a		VEGFR , p38 MAPK , JAK , Src
	AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protei...		VEGFR , p38 MAPK , JAK , Src
T2485	Baricitinib	INCB028050,LY3009104	Tyrosine Kinases , JAK , Chk
	Baricitinib (INCB028050) is an orally bioavailable inhibitor of Janus kinases 1 and 2 (JAK1/2), with potential anti-inflammatory, immunomodulating and antineoplastic activities.		Tyrosine Kinases , JAK , Chk
T12266L2	Ilginatinib hydrochloride	NS-018 hydrochloride	Tyrosine Kinases , JAK
	Ilginatinib hydrochloride (NS-018 hydrochloride) is a highly active and orally bioavailable inhibitor of JAK2.		Tyrosine Kinases , JAK
T12266L	Ilginatinib maleate	NS-018 maleate	Tyrosine Kinases , JAK
	Ilginatinib maleate (NS-018 maleate) is a highly active and orally bioavailable inhibitor of JAK2.		Tyrosine Kinases , JAK
T3620	Solcitinib	GLPG-0778,GSK-2586184	JAK
	Solcitinib (GLPG-0778) (GSK2586184, GLPG0778) is a JAK1 inhibitor. Solcitinib may be potentially used for the treatment of psoriasis, ulcerative colitis, and systemic lupus erythematosus.		JAK
T1849	Momelotinib	CYT11387,CYT387,LM-1149	Apoptosis , JAK , Autophagy
	Momelotinib (LM-1149) is an orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with IC50 of 11 nM/18 nM. JAK1/2 inhibitor CYT387 competes with JAK1/2 for ATP binding, which may result in inhib...		Apoptosis , JAK , Autophagy
T8742	G5-7	JAK2 inhibitor G5-7	Apoptosis , JAK
	JAK2 inhibitor G5-7 (JAK2 inhibitor G5-7) is an orally active JAK2 inhibitor, selectively inhibits JAK2–mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5-7 has the potential for g...		Apoptosis , JAK
T1829	Ruxolitinib	INCB018424,(R)-Ruxolitinib	Apoptosis , Mitophagy , Tyrosine Kinases , JAK , Autophagy
	Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective. Rixolitinib exhibits antitumor activity and induces autophagy and apoptosis.
T22338	2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide	GDC046	Others , JAK
	2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity, physicochemical properties and pharmacokinetic profile.		Others , JAK
T8719	SC99		Apoptosis , JAK , STAT
	SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activiti...		Apoptosis , JAK , STAT

Compounds

Synonym: Janus-Associated Kinase Inhibitor I,JAK Inhibitor,CMP 6,JAK Inhibitor I

Target: Tyrosine Kinases, JAK

Target: PLK, JAK, BTK

Target: Tyrosine Kinases, Histone Methyltransferase, JAK

SAR-20347

T4210

Synonym: SAR20347

Target: Tyrosine Kinases, JAK

Target: Apoptosis, JAK, STAT

Povorcitinib phosphate

Target: Apoptosis, JAK, STAT

Brepocitinib

TQ0010

Synonym: PF-06700841

Target: Tyrosine Kinases, JAK

Target: Tyrosine Kinases, JAK

Target: Apoptosis, Virus Protease, JAK, Parasite

Pacritinib

T6020

Synonym: SB1518

Target: FLT, Tyrosine Kinases, JAK

TCS 21311

T17019

Synonym: NIBR3049

Target: GSK-3, JAK, PKC

RGB-286638 free base

T2378

Synonym:

Target: GSK-3, MEK, JAK, CDK

TG101209

T3065

Synonym:

Target: Apoptosis, FLT, c-RET, JAK, Autophagy

RO495

T22416

Synonym: CS-2667

Target: Tyrosine Kinases, JAK

XL019

T3072

Synonym:

Target: Apoptosis, FLT, JAK, PDGFR

AT9283

T3068

Synonym: J-504568

Target: Apoptosis, FLT, JAK, Bcr-Abl, Aurora Kinase, Autophagy

Target: Tyrosine Kinases, JAK

Tofacitinib

T6321

Synonym: Tasocitinib,CP-690550

Target: ROCK, Apoptosis, JAK, Src

JAK2 Inhibitor V

T3042

Synonym: JAK2 Inhibitor V Z3,Z3

Target: JAK

Cerdulatinib

T2487

Synonym: PRT2070,PRT062070

Target: Tyrosine Kinases, JAK, Syk

Brepocitinib P-Tosylate

T12427

Synonym: PF-06700841 P-Tosylate

Target: JAK

Delgocitinib

T15096

Synonym: JTE-052,Corectim（Delgocitinib）

Target: Tyrosine Kinases, JAK

Itacitinib

T3998

Synonym: INCB39110,INCB039110

Target: Tyrosine Kinases, JAK, IFNAR, Interleukin

GLPG0634 analog

T3076

Synonym: GLPG0634 analogue

Target: Tyrosine Kinases, JAK

Gandotinib

T2638

Synonym: LY2784544

Target: VEGFR, FGFR, FLT, JAK

Decernotinib

T2636

Synonym: VX-509,VRT-831509

Target: Tyrosine Kinases, JAK

AMG-47a

T7123

Synonym:

Target: VEGFR, p38 MAPK, JAK, Src

Baricitinib

T2485

Synonym: INCB028050,LY3009104

Target: Tyrosine Kinases, JAK, Chk

Ilginatinib hydrochloride

T12266L2

Synonym: NS-018 hydrochloride

Target: Tyrosine Kinases, JAK

Ilginatinib maleate

T12266L

Synonym: NS-018 maleate

Target: Tyrosine Kinases, JAK

Solcitinib

T3620

Synonym: GLPG-0778,GSK-2586184

Target: JAK

Momelotinib

T1849

Synonym: CYT11387,CYT387,LM-1149

Target: Apoptosis, JAK, Autophagy

G5-7

T8742

Synonym: JAK2 inhibitor G5-7

Target: Apoptosis, JAK

Ruxolitinib

T1829

Synonym: INCB018424,(R)-Ruxolitinib

Target: Apoptosis, Mitophagy, Tyrosine Kinases, JAK, Autophagy

2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide

Target: Apoptosis, JAK, STAT

カタログ番号	製品名	別名	ターゲット
T4672	Brevilin A		Apoptosis , Anti-infection , JAK , STAT , Autophagy
	Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT si...		Apoptosis , Anti-infection , JAK , STAT , Autophagy
TJS1779	Protosappanin A	PTA	NADPH-oxidase , IL Receptor , IκB/IKK , TNF , NF-κB , TLR , ROS , COX , HIV Protease , JAK , NO Synthase , STAT
	Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IÎºB/NF-ÎºB inflammation signal pathway; it exerts anti-neuroinflammatory ...
TN2269	Tetramethylcurcumin		Apoptosis , STAT
	Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and e...		Apoptosis , STAT
T6S1966	Curculigoside	Curculigoside A	Antioxidant , NF-κB , JAK , STAT
	1. Curculigoside (Curculigoside A) can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disord...		Antioxidant , NF-κB , JAK , STAT
T5S0167	Atractylenolide I		IL Receptor , TNF , TLR , JAK , STAT
	1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide...		IL Receptor , TNF , TLR , JAK , STAT
TQ0196	Cucurbitacin I	NSC-521777,JSI-124,Elatericin B	JAK , STAT
	Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2/STAT3 with anti-cancer activity.		JAK , STAT
T4S1499	Ginsenoside Rk1		Apoptosis , Others , NF-κB , PI3K , JAK
	Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures. Ginsenoside Rk1 has an anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB. It also h...		Apoptosis , Others , NF-κB , PI3K , JAK

天然物製品

Brevilin A

T4672

Synonym:

Target: Apoptosis, Anti-infection, JAK, STAT, Autophagy

Protosappanin A

TJS1779

Synonym: PTA

Target: NADPH-oxidase, IL Receptor, IκB/IKK, TNF, NF-κB, TLR, ROS, COX, HIV Protease, JAK, NO Synthase, STAT

Tetramethylcurcumin

TN2269

Synonym:

Target: Apoptosis, STAT

Curculigoside

T6S1966

Synonym: Curculigoside A

Target: Antioxidant, NF-κB, JAK, STAT

Atractylenolide I

T5S0167

Synonym:

Target: IL Receptor, TNF, TLR, JAK, STAT

Cucurbitacin I

TQ0196

Synonym: NSC-521777,JSI-124,Elatericin B

Target: Apoptosis, Others, NF-κB, PI3K, JAK

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04799	IFNAR2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei...
TMPY-05636	G-CSF Protein, Mouse, Recombinant	Mouse	HEK293
	Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPY-04829	G-CSF Protein, Human, Recombinant	Human	HEK293
	Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPK-01071	IL-22RA1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), ...
TMPK-01105	IL-22RA1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), ...
TMPJ-00356	GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth,...
TMPY-05465	IL-20RB Protein, Mouse, Recombinant (His)	Mouse	HEK293
	IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors: cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleu...
TMPY-04711	IL-20RB Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors: cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleu...
TMPY-03086	IL-20RB Protein, Rat, Recombinant (hFc)	Rat	HEK293
	IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors: cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleu...
TMPY-04712	IL-20RB Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors: cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleu...
TMPY-02902	IL-20RB Protein, Rat, Recombinant (His)	Rat	HEK293
	IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors: cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleu...
TMPY-05559	IL-20RB Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	IL20RB belongs to the type II cytokine receptor family. There are two kinds of type II cytokine receptors: cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleu...
TMPJ-00398	IL-12RB2 Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	The IL12 receptor complex, formed by IL12RB1 and IL12RB2, mediates the type I immune responses of various types of lymphocytes. Its ligand, IL12, is a heterodimeric cytokine composed of IL-12p35 and IL-12p40 subunits tha...
TMPJ-00194	IL-20RB Protein, Human, Recombinant (hFc)	Human	Human Cells
	Interleukin-20 receptor subunit beta（IL20RB） is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytoki...
TMPY-02467	ISG15 Protein, Human, Recombinant (mature form)	Human	E. coli
	Interferon-induced 17 kDa protein (ISG15), a 15-kDa protein of unique primary amino acid sequence, functions intracellularly as a ubiquitin homolog and a cytokine that induces production of IFN-gamma and augments NK / ly...
TMPY-02348	ISG15 Protein, Human, Recombinant	Human	E. coli
	Interferon-induced 17 kDa protein (ISG15), a 15-kDa protein of unique primary amino acid sequence, functions intracellularly as a ubiquitin homolog and a cytokine that induces production of IFN-gamma and augments NK / ly...
TMPY-01640	IFNAR2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei...
TMPY-00139	IFNAR2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei...
TMPY-01642	IFNAR2 Protein, Human, Recombinant (His)	Human	HEK293
	Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei...
TMPY-00813	G-CSF Protein, Human, Recombinant (hFc)	Human	HEK293
	Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...